Chronic Traumatic Encephalopathy (CTE) is a progressive degenerative disease of the brain found in athletes (and others) with a history of repetitive head trauma. This week, the family of NFL football star Frank Gifford revealed an autopsy after his death diagnosed him with CTE. CTE has been known to affect boxers since the 1920s and was once called "Dementia pugilistica". These changes in the brain can begin months, years, or even decades after the last brain trauma or end of active athletic involvement. The brain degeneration is associated with memory loss, confusion, impaired judgment, impulse control problems, aggression, depression, and, eventually, progressive dementia.